Data modeling and data communication in GenomEUtwin.

نویسندگان

  • Jan-Eric Litton
  • Juha Muilu
  • Ann Björklund
  • Anne Leinonen
  • Nancy L Pedersen
چکیده

Database infrastructure has become a critical component for competitive life sciences research and discovery. The explosion of data requires that the data are properly loaded, accessed, managed, queried, analyzed, and shared with others. The key purpose of the population-based twin cohorts housed at different institutions in Europe is to gather an extremely large quantity of information from their twin populations, and share it. Longitudinal research over a long period of time, hopefully generations, demands completely new methods and systems to handle the gathering of information and storing. These cohorts bring to the fore problems concerning the need for a standardization of research data and a computer and storage strategy. In the following we describe the preliminary strategy being implemented in the Database Core of GenomEUtwin.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Analysis of genetic variation in the GenomEUtwin project.

Multiallelic short tandem repeat polymorphisms, or microsatellites, are useful markers in genome wide scans to identify chromosomal regions containing genes underlying disease loci. The biallelic single nucleotide polymorphism (SNP) can be used to fine map previously identified large candidate regions or to test functional candidate genes by association analysis. In the GenomEUtwin project the ...

متن کامل

The Effectiveness of Social Stories with Video Modeling on Communication Skills of Children with Autism Spectrum Disorder (ASD)

Background & purpose: Autism spectrum disorder is a developmental neurological disorder characterized by impairment in social and communication interactions and repetitive behaviors.  The increasing prevalence of this disorder has raised the need for research on its characteristics and treatment methods.  The aim of this study was to investigate the effect of social stories using video modeling...

متن کامل

Mediating Role of Coping Strategies in the Relationship between Family Communication Pattern and Addiction Potential

Objective: The aim of this study was to investigate the mediating role of coping strategies in the relationship between family communication pattern and addiction potential in the youth. Method: The present study was descriptive-correlational of structural equation modeling type. The statistical population of the present study included members of the Youth Organization of the Iranian Red Cresce...

متن کامل

Longevity studies in GenomEUtwin.

Previous twin studies have indicated that approximately 25% of the variation in life span can be attributed to genetic factors and recent studies have also suggested a moderate clustering of extreme longevity within families. Here we discuss various definitions of extreme longevity and some analytical approaches with special attention to the challenges due to censored data. Lexis diagrams are p...

متن کامل

Bayesian Modeling Based on Data from the Internet of Things

The Internet of Things is suggested as the upcoming revolution in the Information and communication technology due to its very high capability of making various businesses and industries more productive and efficient. This productivity comes from the emergence of innovation and the introduction of new capabilities for businesses. Different industries have shown varying reactions to IOT, but wha...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Twin research : the official journal of the International Society for Twin Studies

دوره 6 5  شماره 

صفحات  -

تاریخ انتشار 2003